Aspergilloma most commonly develops in cavities created by which disease?

Aspergilloma most commonly develops in cavities created by which disease?

• A. Pneumonia
• B. COPD without cavities
• C. Lung cancer
• D. Tuberculosis

Answer: (D)

Aspergilloma forms when Aspergillus colonizes a preexisting lung cavity, creating a mobile fungus ball within that space. The cavities that provide the best niche are typically those left by healed tuberculosis, which produces fibrocavitary lesions, often in the upper lobes. This setting—a long-standing cavity with air-filled space and relatively stable walls—allows the fungus to grow without invading surrounding tissue. While other diseases can also cause cavities, tuberculosis creates the classic, most common source of cavities for aspergilloma to develop.

Aspergilloma forms when Aspergillus colonizes a preexisting lung cavity, creating a mobile fungus ball within that space. The cavities that provide the best niche are typically those left by healed tuberculosis, which produces fibrocavitary lesions, often in the upper lobes. This setting—a long-standing cavity with air-filled space and relatively stable walls—allows the fungus to grow without invading surrounding tissue. While other diseases can also cause cavities, tuberculosis creates the classic, most common source of cavities for aspergilloma to develop.